The DuraSite system can be customized to deliver a wide variety of potential drug agents. DuraSite is a drug delivery vehicle that stabilizes small molecules in a polymeric mucoadhesive matrix. The topical ophthalmic solution can be described as a gel forming drop, which extends the residence time of the drug relative to conventional eye drops.
The addition of the DuraSite drug delivery vehicle to azithromycin increases the drug's contact time with the ocular surface for several hours. This permits products like AzaSite to achieve high tear-film and conjunctival concentrations of the antibiotic azithromycin. This increased residence time allows the drug to be administered over a longer period of time, minimizing dosing frequency and potentially reducing adverse side effects.